Thomas J Walsh Selected Research

posaconazole

1/2021	Pharmacodynamics of Posaconazole in Experimental Invasive Pulmonary Aspergillosis: Utility of Serum Galactomannan as a Dynamic Endpoint of Antifungal Efficacy.
9/2020	Modeling Invasive Aspergillosis: How Close Are Predicted Antifungal Targets?
3/2020	Posaconazole Alone and in Combination with Caspofungin for Treatment of Experimental Exserohilum rostratum Meningoencephalitis: Developing New Strategies for Treatment of Phaeohyphomycosis of the Central Nervous System.
1/2019	A non-randomized trial to assess the safety, tolerability, and pharmacokinetics of posaconazole oral suspension in immunocompromised children with neutropenia.
9/2013	Hyperthermia sensitizes Rhizopus oryzae to posaconazole and itraconazole action through apoptosis.
3/2013	Tacrolimus enhances the potency of posaconazole against Rhizopus oryzae in vitro and in an experimental model of mucormycosis.
9/2011	Antifungal activity of posaconazole and granulocyte colony-stimulating factor in the treatment of disseminated zygomycosis (mucormycosis) in a neutropaenic murine model.
6/2009	Recent advances in the management of mucormycosis: from bench to bedside.
1/2007	Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia.
1/2007	Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: an externally controlled trial.

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Thomas J Walsh Research Topics

Disease

93	Infections 05/2022 - 03/2002
48	Aspergillosis 01/2021 - 01/2002
42	Invasive Fungal Infections 01/2021 - 01/2002
41	Mycoses (Diseases, Fungus) 01/2022 - 01/2002
35	Candidiasis (Moniliasis) 11/2018 - 05/2002
29	Invasive Pulmonary Aspergillosis 01/2021 - 01/2002
28	Invasive Candidiasis 01/2019 - 12/2002
26	Body Weight (Weight, Body) 10/2021 - 01/2002
26	Neutropenia 10/2021 - 01/2002
20	Candidemia 01/2021 - 03/2002
18	Mucormycosis 01/2021 - 06/2009
17	Neoplasms (Cancer) 01/2018 - 02/2005
12	Hematologic Neoplasms (Hematological Malignancy) 01/2020 - 10/2004
10	Bacteremia 05/2022 - 05/2010
9	Zygomycosis (Phycomycosis) 09/2011 - 04/2005
8	Meningoencephalitis 02/2021 - 01/2008
8	Lung Injury 09/2020 - 01/2002
8	Pulmonary Aspergillosis 09/2013 - 01/2002
7	Diabetes Mellitus 01/2018 - 01/2009
7	Fever (Fevers) 10/2015 - 01/2002
6	Sepsis (Septicemia) 10/2021 - 01/2009
5	Leukemia 01/2022 - 04/2003
5	Endophthalmitis (Ophthalmia) 01/2021 - 04/2014
5	Infertility (Sterility) 01/2021 - 10/2007
5	Pulmonary Infarction 01/2016 - 01/2002
5	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2015 - 04/2006
5	Graft vs Host Disease (Graft-Versus-Host Disease) 06/2015 - 01/2004
5	Inflammation (Inflammations) 01/2011 - 06/2003
5	Chronic Granulomatous Disease 01/2011 - 06/2005
4	Infarction (Infarctions) 09/2020 - 06/2009
4	Pneumonia (Pneumonitis) 01/2020 - 05/2010
4	Male Infertility (Male Sterility) 10/2019 - 03/2009
4	Fungal Meningitis 01/2019 - 03/2013
4	Communicable Diseases (Infectious Diseases) 01/2018 - 07/2009
4	Wounds and Injuries (Trauma) 10/2017 - 05/2010
3	Phaeohyphomycosis 02/2021 - 12/2015
3	Penile Induration (Peyronie's Disease) 12/2020 - 03/2011
3	Soft Tissue Infections 01/2020 - 01/2010
3	Fungemia 01/2020 - 12/2004
3	Osteomyelitis 11/2019 - 11/2012
3	Drug-Related Side Effects and Adverse Reactions 03/2018 - 05/2008
3	Bacterial Pneumonia 01/2018 - 01/2009
3	Bacterial Infections (Bacterial Infection) 12/2017 - 07/2009
3	Critical Illness (Critically Ill) 01/2017 - 07/2009
3	scedosporiosis 01/2016 - 03/2002

Drug/Important Bio-Agent (IBA)

46	Amphotericin B (Amphotericin)FDA LinkGeneric 09/2020 - 01/2002
34	Antifungal AgentsIBA 09/2020 - 07/2002
33	EchinocandinsIBA 01/2022 - 01/2002
28	Voriconazole (Vfend)FDA LinkGeneric 09/2020 - 01/2002
25	liposomal amphotericin B FDA Link 02/2021 - 01/2002
23	TriazolesIBA 02/2021 - 07/2002
22	Pharmaceutical PreparationsIBA 12/2020 - 01/2002
21	galactomannanIBA 01/2021 - 01/2002
20	Micafungin (FK463)FDA Link 02/2021 - 06/2002
19	Fluconazole (Zonal)FDA LinkGeneric 01/2016 - 06/2003
18	Biomarkers (Surrogate Marker)IBA 01/2021 - 02/2006
14	posaconazole FDA Link 01/2021 - 01/2004
14	Caspofungin (Cancidas)FDA Link 09/2020 - 01/2002
14	Anti-Bacterial Agents (Antibiotics)IBA 03/2020 - 10/2004
11	isavuconazoleIBA 02/2021 - 11/2014
10	Anidulafungin FDA Link 09/2020 - 09/2004
9	Deoxycholic Acid (Sodium Deoxycholate)IBA 09/2020 - 01/2002
9	EnzymesIBA 01/2011 - 08/2004
8	AntigensIBA 09/2017 - 01/2002
7	Methylprednisolone FDA LinkGeneric 03/2020 - 06/2010
7	LipidsIBA 12/2013 - 11/2007
6	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2017 - 02/2005
5	Testosterone (Sustanon)FDA Link 01/2021 - 04/2012
5	deoxycholate drug combination amphotericin BIBA 10/2018 - 10/2006
5	IronIBA 08/2012 - 04/2008
4	Carbapenems (Carbapenem Antibiotics)IBA 05/2022 - 09/2003
4	ceftazidime drug combination avibactamIBA 05/2022 - 01/2017
4	ibrexafungerpIBA 09/2020 - 01/2017
4	Proteins (Proteins, Gene)FDA Link 06/2014 - 08/2008
4	AzolesIBA 12/2013 - 02/2005
3	Vancomycin FDA LinkGeneric 10/2021 - 09/2010
3	Anti-Infective Agents (Microbicides)IBA 10/2021 - 05/2014
3	Levofloxacin (Levaquin)FDA Link 10/2021 - 10/2015
3	ProdrugsIBA 01/2021 - 01/2016
3	MannansIBA 11/2019 - 01/2007
3	SuspensionsIBA 01/2019 - 08/2002
3	Aztreonam FDA LinkGeneric 01/2019 - 05/2010
3	Triamcinolone (Aristocort)FDA Link 01/2019 - 04/2014
3	Polymyxin B (Aerosporin)FDA LinkGeneric 07/2018 - 01/2017
3	PolyenesIBA 11/2017 - 12/2003

Therapy/Procedure

117	Therapeutics 05/2022 - 01/2002
10	Salvage Therapy 06/2009 - 05/2003
9	Hematopoietic Stem Cell Transplantation 07/2017 - 11/2004
8	Drug Therapy (Chemotherapy) 10/2021 - 01/2004
8	Transplantation 10/2017 - 01/2004
6	Central Venous Catheters 03/2018 - 09/2010
6	Organ Transplantation 07/2017 - 12/2004
5	Vascular Access Devices (Arterial Line) 10/2021 - 03/2002
5	Injections 12/2020 - 10/2004
5	Length of Stay 03/2020 - 12/2004
4	Catheters 01/2020 - 03/2002
4	Stem Cell Transplantation 06/2015 - 10/2004
3	Critical Care (Surgical Intensive Care) 01/2021 - 12/2013
3	Lasers (Laser) 01/2021 - 01/2017
3	Intravitreal Injections 01/2019 - 04/2014